Jan Lubinski Selected Research

Ovariectomy (Oophorectomy)

1/2022	Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal.
1/2022	The impact of oophorectomy on survival from breast cancer in patients with CHEK2 mutations.
6/2021	Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers.
1/2021	Survival from breast cancer in women with a BRCA2 mutation by treatment.
1/2020	Does preventive oophorectomy increase the risk of depression in BRCA mutation carriers?
11/2019	A comparison of ovarian cancer mortality in women with BRCA1 mutations undergoing annual ultrasound screening or preventive oophorectomy.
6/2019	Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers.
4/2018	Predictors of survival for breast cancer patients with a BRCA1 mutation.
1/2018	Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation.
1/2018	Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers.

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Jan Lubinski Research Topics

Disease

91	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2002
80	Neoplasms (Cancer) 03/2022 - 11/2002
40	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 01/2006
12	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 11/2002
8	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2021 - 11/2006
6	Carcinoma (Carcinomatosis) 01/2022 - 11/2002
6	Prostatic Neoplasms (Prostate Cancer) 12/2019 - 04/2013
4	Triple Negative Breast Neoplasms 01/2019 - 01/2011
3	Fallopian Tube Neoplasms 01/2022 - 07/2006
3	Obesity 01/2019 - 05/2010
3	Ovarian Epithelial Carcinoma 01/2018 - 05/2014
3	Renal Cell Carcinoma (Grawitz Tumor) 11/2017 - 06/2009
3	Endometrial Neoplasms (Endometrial Cancer) 09/2015 - 01/2007
2	Microsatellite Instability 01/2021 - 11/2002
2	Genetic Risk Score 01/2020 - 05/2015
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2018 - 01/2018
2	Familial Breast Cancer 11/2017 - 02/2015
2	Chromosomal Instability (Chromosome Stability) 11/2017 - 11/2002
2	Pathologic Complete Response 10/2016 - 01/2010
2	Carcinogenesis 09/2016 - 02/2014
2	Hypersensitivity (Allergy) 11/2015 - 12/2013
2	Hypoxia (Hypoxemia) 08/2013 - 11/2009
2	Inflammation (Inflammations) 05/2013 - 04/2010
2	Pituitary Neoplasms (Pituitary Adenoma) 10/2008 - 03/2007
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	Turcot syndrome 01/2022
1	Neurodevelopmental Disorders 01/2022
1	Schizophrenia (Dementia Praecox) 01/2022
1	Endometriosis 01/2022
1	Chromosome Fragility 01/2019

Drug/Important Bio-Agent (IBA)

31	Estrogen ReceptorsIBA 03/2022 - 10/2010
20	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 05/2005
15	Proteins (Proteins, Gene)FDA Link 03/2022 - 11/2002
10	Oral ContraceptivesIBA 01/2022 - 12/2002
10	Tamoxifen FDA LinkGeneric 09/2015 - 05/2006
8	Hormones (Hormone)IBA 02/2016 - 10/2008
7	ORALIT (ORS)IBA 03/2022 - 10/2005
6	Progesterone Receptors (Progesterone Receptor)IBA 03/2022 - 10/2011
6	Genetic Markers (Genetic Marker)IBA 01/2019 - 12/2010
6	Biological ProductsIBA 12/2017 - 01/2006
6	Transcription Factors (Transcription Factor)IBA 11/2017 - 11/2009
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2016
5	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2017 - 05/2010
4	Phenobarbital (Luminal)FDA Link 01/2020 - 01/2011
4	Estrogens (Estrogen)FDA Link 01/2018 - 10/2008
4	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2017 - 05/2010
4	MicroRNAs (MicroRNA)IBA 01/2016 - 07/2013
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2015 - 12/2008
4	IronIBA 01/2015 - 04/2010
3	ChromatinIBA 01/2022 - 01/2015
3	human ERBB2 proteinIBA 01/2020 - 12/2011
3	Prostate-Specific Antigen (Semenogelase)IBA 12/2019 - 01/2018
3	olaparibIBA 01/2019 - 05/2010
3	Progesterone FDA LinkGeneric 01/2018 - 10/2008
3	CarcinogensIBA 01/2018 - 11/2006
3	Cisplatin (Platino)FDA LinkGeneric 10/2016 - 01/2011
3	3' Untranslated Regions (3' UTR)IBA 01/2016 - 01/2014
3	PlatinumIBA 01/2015 - 05/2010
3	SeleniumIBA 11/2013 - 05/2005
3	Resistant StarchIBA 12/2012 - 12/2008
3	Starch (Cornstarch)IBA 12/2012 - 12/2008
2	Contraceptive Agents (Contraceptives)IBA 01/2022 - 01/2011
2	5' Untranslated Regions (5' UTR)IBA 02/2021 - 12/2007
2	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021 - 06/2013
2	A-Form DNA (A-DNA)IBA 01/2019 - 05/2006
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 05/2010
2	Insulin (Novolin)FDA Link 01/2019 - 08/2012
2	SmokeIBA 01/2018 - 03/2009
2	Protein Isoforms (Isoforms)IBA 01/2018 - 11/2002
2	Transforming Growth Factor-beta Type II ReceptorIBA 10/2016 - 01/2016
2	NucleotidesIBA 09/2016 - 04/2015
2	Folic Acid (Vitamin M)FDA LinkGeneric 09/2016 - 04/2010
2	GonadotropinsIBA 03/2016 - 03/2015
2	LuciferasesIBA 07/2015 - 04/2013
2	Nonsense Codon (Nonsense Mutation)IBA 03/2015 - 11/2009
2	Aurora Kinase AIBA 01/2015 - 07/2007
2	Cyclin D1IBA 04/2013 - 03/2008
2	Insulin-Like PeptidesIBA 08/2012 - 06/2011
2	EnzymesIBA 04/2011 - 08/2010
2	8-Hydroxy-2'-DeoxyguanosineIBA 11/2009 - 11/2009
2	aryl hydrocarbon receptor-interacting proteinIBA 10/2008 - 03/2007
2	Coffee FDA Link 01/2006 - 01/2006
1	Ion Channels (Ion Channel)IBA 01/2022
1	CalciumIBA 01/2022
1	Sp4 Transcription FactorIBA 01/2022
1	Glutamate Receptors (Glutamate Receptor)IBA 01/2022
1	dimemorfan (AT 17)IBA 01/2022
1	Histone Deacetylases (Histone Deacetylase)IBA 02/2021
1	Kallikreins (Kallikrein)IBA 12/2019

Therapy/Procedure

25	Ovariectomy (Oophorectomy) 01/2022 - 10/2005
10	Therapeutics 04/2018 - 10/2008
8	Mastectomy (Mammectomy) 06/2021 - 03/2008
7	Drug Therapy (Chemotherapy) 04/2018 - 10/2003
6	Hormone Replacement Therapy (Therapy, Hormone Replacement) 06/2021 - 01/2006
5	Salpingo-oophorectomy 01/2020 - 07/2006
3	Prophylactic Mastectomy 11/2013 - 03/2008
2	Neoadjuvant Therapy 10/2016 - 01/2010
2	Tubal Sterilization (Tubal Ligation) 02/2009 - 01/2007
1	Contraception (Birth Control) 01/2022
1	Intrauterine Devices (Intrauterine Device) 01/2022